Diane Noomin was born in Brooklyn, New York, in 1947 and attended the High School of Music and Art, Brooklyn College and Pratt Institute.
She is the creator of DiDi Glitz and editor of the Twisted Sisters anthologies of women cartoonists. One of the early contributors to Wimmen's Comics, Noomin created the first issue of Twisted Sisters Comics with Aline Kominsky Crumb in 1976.
Noomin's work has also been published in a number of books, magazines and comic books including Weirdo, Young Lust, Arcade:The Comics Review, Lemme Outta Here, Dangerous Drawings, Mind Riot,The Comics Journal/Special Editions, The New Comics Anthology,True Glitz, The Nose and The Nation.
In 1981, she collaborated on the musical comedy "I'd Rather Be Doing Something Else:The DiDi Glitz Story" with the San Francisco- based women's theater group, Les Nickelettes.
Noomin has been nominated for Harvey and Eisner awards and was given the Ink Pen award in 1994.
She has curated and shown work in the Twisted Sister's Show at White Columns Gallery in 1996, The Museum of Cartoon Art of San Francsico in 1995 and La Luz de Jesus Gallery in Los Angeles in 1991.
In 1994, Noomin had a solo exhibition at the Little Frankenstein Gallery in San Francisco.
She lives in Connecticut with her husband, cartoonist Bill Griffith, and 3 cats.